The Lancet Rules Russian COVID-19 Vaccine "Safe And Effective"
Posted by freedomforall 4 years, 7 months ago to Technology
Trial results reported Friday by the Lancet, the British medical journal responsible for publishing some of the earliest research on the coronavirus, found that Russia's Gameleya Institute-developed SARS-CoV-2 vaccine is both effective and safe, though scientists cautioned that long-term study is still required.
The vaccine, the researchers found, produced an antibody response in all test subjects while causing no serious adverse effects. The results mark the latest stamp of legitimacy for the vaccine developed by the world-reknowned Gameleya Institute, and show how the early and intense skepticism expressed by some in the West might have been premature.
The vaccine, the researchers found, produced an antibody response in all test subjects while causing no serious adverse effects. The results mark the latest stamp of legitimacy for the vaccine developed by the world-reknowned Gameleya Institute, and show how the early and intense skepticism expressed by some in the West might have been premature.
When it comes to the often long boring slogging of quality control and assurance, testing, and the manufacture of reliable products, maybe, or not.
Unfair stereotype? Yes but still.
When a vaccine typically takes 3, 4, or 5 years to design, test, and produce, then I hear that the Russians have got one in production after six months, I think- include me out for a few years.
They have a lot to offer, but I'm not sure they can trust us any more than we are able to de-program ourselves and trust them.
I agree on the vaccine. I'd rather take HCQ and let the more gullible get the vaccines.
As to a vaccine, all it has to be is effective enough to keep you from falling ill with corona, an not have bad side effects. I am not sure that the normal that phase 3 trials give enough assurances of that, or actually give unnecessary assurances of it. So the Russians might be right after all. We will have to see
Normally you do Phase I, analyze the results, Phase II, analyze the results, Phase III, analyze the results get approval and begin production. The "Warp speed" program has overlapped the phases, planning and starting the next phase while still finishing the prior one. The vaccine is in production even though phase III is a bit over a month into it. Actually, I believe, there are three different vaccines in production -- so that if the are approved they will go out right away.
And they are talking about due to an emergency that we separate safe from effective. If the vaccine is safe but we are not sure off how effective it is, it could be conditionally approved.
I've always thought that if we needed an FDA (and those here would certainly challenge that), their mission should be limited to safe. The marketplace can deal with effective.
I also know that many here, for good reasons, do not like vaccines. They do trigger the immune system and stuff can happen when you do that, but in this case, I'm ready to roll up my sleeve if we have one that seems safe and looks like it is generating a decent immune response.
Back last century I was in testing for reliability and life of electronic components. There was something called 'accelerated' life tests. The name had the right 'cache'. Then a claim is made that testing at 50C higher temperature over 6 months was the equivalent of operating conditions for 6 years, well there is some, weak, evidence for that.
The probability of a bad reaction to a vaccine decreases relatively rapidly through time. Yes, it's possible that you would be just fine but 20 year later have a reaction but not likely.
We've now been several months since the small group of phase I subjects were injected and now there are thousands of phase III. Reactions seem typical, injection soreness, mild fever -- you are activating the immune system after all.
I have some of the risk factors so when a vaccine that doesn't have unusual side effects and even seems to be working is available, I want it. Covid-19 does not seem like something I want to get immunity to by catching it and surviving.
Components- capacitors, resistors, diodes, transistors, and that ilk. But not inductors, transformers.., I think as these were not produced on the same scale. I was in civil aviation and recall that military planes got older inferior devices as the testing specified by the agencies took longer and was more stringent. There were ways around that I think. As well, for similar reasons, military equipment had a lifetime double or more that of civil stuff.
As WS says, extrapolating from tests to life takes some thought and guessing. I suppose the basic ideas on safety testing are much the same in pharmaceuticals. Yes many processes can be speeded up, maybe you do not need to test for five years, or two, but how many? If there should be a bad reaction that takes six months to detect, and you test for three months, then what? The answer could be in individual risk analysis, but in this case I'd go for HCQ.
You would know about the 'bathtub curve'.
Way off topic but some good news-
Stella Immanuel, the Texas doc originally from Nigeria, who joined front-line-doctors in saying- HCQ works and is safe, was accused of something or other in a complaint to the Texas Medical Board -- now cleared by the Board.
And these institutions are the ones that push the regs, in my opinion, to preclude equitable competition. IE: every level of cost of compliance must be accounted for as a "profitable" step toward production distribution. Similar in auto safety compliance testing.
Can't remember how many times I have heard "there's a law....", "this shouldn't happen"... and i ask; Have you ever seen one sheet of paper stop a bullet?
https://www.emmanuelsblog.com.ng/2020...
Re: Front Line COVID-19 Critical Care (FLCCC) Working Group... For prophylaxis, the FLCCC recommends:
Vitamin C — 500 mg
Quercetin — 250 mg to 500 mg
Zinc — 75-100 mg/day (acetate, gluconate or picolinate). Zinc lozenges are preferred. After one month, reduce the dose to 30 mg to 50 mg per day
Melatonin (slow release) — Begin with 0.3 mg and increase as tolerated to 2 mg at night
Vitamin D3 — 1,000 to 4,000 IUs per day
See:
-- https://articles.mercola.com/sites/ar...
-- https://articles.mercola.com/sites/ar...
That should have you covered...
https://www.youtube.com/watch?v=V8Ks9...
Personally, don't need it. Along with an overwhelming majority of people, we have a vaccine that can produce antibodies. It is called a well-functioning immune system, operating in a healthy body.
Make the vaccine available to people who need it. Let people who are susceptible/compromised wear masks and hide out. Let the vast majority of people get back to life, which we should've done on day 1.
Others being afraid does not compel me to servitude. However, others being afraid does ruin the economy. and compromise general happiness. This fear mongering is overblown, and stems from only two sources:
1. Ignorant people, and
2. Evil people parochially seeking to ruin the world, to ensure Trump is not re-elected, such that they gain power.
If it were planned, they would have well guessed the hysteria and the damage we are doing to ourselves. So much spying, many contacts, and good analysis too.
My reading is that there were different mutations arriving in Europe than in N.America.
The question is: "Do you support compelling me and countless other based on your own decision?"
I generally don't take flu shots because the mild side effects are generally about as bad as I get flu. On the other hand I got the whole set of pneumonia shots. Losing a 26 year old healthy employee to H1N1 back in 2009 made it clear to me just how useless modern medicine is if your lungs are full and you can't absorb oxygen.
I'm taking 5000IU of D every day and am generally healthy. I told Jan that I couldn't remember the last time I was home sick. She reminded me of a serious gout attack that kept me home for several days -- and I replied "that was in the 1990's".
1) vaccination,
2) being fortunate,
3) CoronaVirus infection,
4) acting like aliens have invaded our planet, cowering behind masks, hand sanitizer and proximity, sacrificing recreation and playing sports (care NOTHING about spectator sports) and destroying our economy.
Am I giving Russia too much credit here?
Leaders are the problem in most countries.
And effective is measured as developing anti-bodies.
Meanwhile, Dr. Peter Attia had a fellow on to explain the difference between "antibodies" and "antibodies".
There are 2 possible antibodies. The kind that TAG the virus for destruction/pickup/macrophages.
And the kind that tag the SPIKE, which make it inert, because it can no longer get into our cells.
(My summary, not all viruses have a spike protein, but the concept is the same, the TAG covers the part that enables it to enter our cells. This is the GOLD STANDARD antibody!)
I am not sure we know which kind of antibodies these people are making.
Also, this virus appears to be able to Trigger a Cytokine Storm. This means PRIOR Immunity, even from a Vaccine could trigger this. This is what hits people so hard the second time in Dengue Fever. It is ALSO WHY the first SARS vaccine development was STOPPED. Because it caused this in the monkeys who were then exposed to the live virus!
We are PLAYING with Fire! Kudos to the scientists for hitting certain goals. Hopefully we are NOT too smart for our own good here...
"We will bury you."
IMO, he is THEIR Trump. The majority of what he is doing is actually helping the average Russian. Albeit with a slight criminal bent...
In Russian Politics, you either play for keeps or you are summarily destroyed/killed. I think he is playing for keeps.
But having been there a few times, Russia has really been improving under his watch.